活動実績

研究支援

• 生命科学統合支援センター利用実績
• 2023年度登録者数、依頼件数
• 2023年度機器稼働状況
• 生命科学統合支援センター利用者の研究成果
年度毎研究成果リスト
2023年度 (41件) 2022年度 (52件) 2021年度 (48件) 過去の実績
1. Pathological evaluation of a fluoropolymer-based drug-eluting stent in an arteriovenous graft outflow venous stenosis. Suemitsu K, Iida O, Torii S, Hata Y, Toyoshima T, Izumi M. J Vasc Surg Cases Innov Tech. 2024 Feb 8;10(3):101447.
2. Blood compatibility of poly(propylene glycol diester) and its water structure observed by differential scanning calorimetry and (2)H-nuclear magnetic resonance spectroscopy. Mochizuki A, Udagawa A, Miwa Y, Oda Y, Yoneyama K, Okuda C. J Biomater Sci Polym Ed. 2024 Jun;35(8):1258-1272.
3. SOD2 orchestrates redox homeostasis in intervertebral discs: A novel insight into oxidative stress-mediated degeneration and therapeutic potential. Tamagawa S, Sakai D, Nojiri H, Nakamura Y, Warita T, Matsushita E, Schol J, Soma H, Ogasawara S, Munesada D, Koike M, Shimizu T, Sato M, Ishijima M, Watanabe M. Redox Biol. 2024 May;71:103091.
4. Rare CRHR2 and GRM8 variants identified as candidate factors associated with eating disorders in Japanese patients by whole exome sequencing. Oka A, Hadano S, Ueda MT, Nakagawa S, Komaki G, Ando T. Heliyon. 2024 Mar 26;10(8):e28643.
5. Cross-contamination of CRISPR guides and other unrelated nucleotide sequences among commercial oligonucleotides. Arakawa H, Miura H, Quadros RM, Ohtsuka M, Gurumurthy CB. Nucleic Acids Res. 2024 Apr 12;52(6):3137-3145.
6. Mutational, immune microenvironment, and clinicopathological profiles of diffuse large B-cell lymphoma and follicular lymphoma with BCL6 rearrangement. Carreras J, Ikoma H, Kikuti YY, Miyaoka M, Hiraiwa S, Tomita S, Kondo Y, Ito A, Nagase S, Miura H, Kawada H, Roncador G, Campo E, Hamoudi R, Nakamura N. Virchows Arch. 2024 Apr;484(4):657-676.
7. Biological differences of three paclitaxel- and sirolimus-coated balloons on coronary lesions in a rabbit model. Aihara K, Torii S, Ito M, Koseki K, Shiozaki M, Sato Y, Nakamura N, Yoshikawa A, Ikari Y, Nakazawa G. EuroIntervention. 2024 Mar 18;20(6):e389-e398.
8. Effect of PCDH19 missense mutations on cell-to-cell proximity and neuronal development under heterotypic conditions. Motosugi N, Sugiyama A, Otomo A, Sakata Y, Araki T, Hadano S, Kumasaka N, Fukuda A. PNAS Nexus. 2024 Feb 8;3(3):pgae060.
9. Diphenyl-tetrazol-propanamide Derivatives Act as Dual-Specific Antagonists of Platelet CLEC-2 and Glycoprotein VI. Watanabe N, Shinozaki Y, Ogiwara S, Miyagasako R, Sasaki A, Kato J, Suzuki Y, Fukunishi N, Okada Y, Saito T, Iida Y, Higashiseto M, Masuda H, Nagata E, Gotoh K, Amino M, Tsuji T, Morita S, Nakagawa Y, Hirayama N, Inokuchi S. Thromb Haemost. 2024 Mar;124(3):203-222.
10. ISSLS PRIZE in Basic Science 2024: superiority of nucleus pulposus cell- versus mesenchymal stromal cell-derived extracellular vesicles in attenuating disc degeneration and alleviating pain. Ambrosio L, Schol J, Ruiz-Fernandez C, Tamagawa S, Soma H, Tilotta V, Di Giacomo G, Cicione C, Nakayama S, Kamiya K, Papalia R, Sato M, Vadal? G, Watanabe M, Denaro V, Sakai D. Eur Spine J. 2024 Feb 28.
11. The GLP-1 receptor agonist exenatide improves recovery from spinal cord injury by inducing macrophage polarization toward the M2 phenotype. Noguchi T, Katoh H, Nomura S, Okada K, Watanabe M. Front Neurosci. 2024 Feb 15;18:1342944.
12. Investigating the immunological function of alpha-2-glycoprotein 1, zinc-binding in regulating tumor response in the breast cancer microenvironment. Hanamura T, Yokoyama K, Kitano S, Kagamu H, Yamashita M, Terao M, Okamura T, Kumaki N, Hozumi K, Iwamoto T, Honda C, Kurozumi S, Richer JK, Niikura N. Cancer Immunol Immunother. 2024 Feb 13;73(3):42.
13. Nucleotide alterations in the HLA-C class I gene can cause aberrant splicing and marked changes in RNA levels in a polymorphic context-dependent manner. Mizutani A, Suzuki S, Shigenari A, Sato T, Tanaka M, Kulski JK, Shiina T. Front Immunol. 2024 Jan 24;14:1332636.
14. Cyclic-di-AMP confers an invasive phenotype on Escherichia coli through elongation of flagellin filaments. Tanaka R, Imai J, Sugiyama E, Tsubaki S, Hozumi K, Tsugawa H. Gut Pathog. 2024 Jan 24;16(1):6.
15. Elevation of inositol pyrophosphate IP(7) in the mammalian spinal cord of amyotrophic lateral sclerosis. Ito M, Fujii N, Kohara S, Tanaka M, Takao M, Mihara B, Saito Y, Mizuma A, Nakayama T, Netsu S, Suzuki N, Kakita A, Nagata E. Front Neurol. 2024 Jan 11;14:1334004.
16. Using hemoglobin vesicles to treat operative hemorrhagic shock after pneu- monectomy in dog models: an experimental study. Nakano K, Kohno M, Onozawa H, Hashimoto R, Oiwa K, Masuda R, Yamaguchi M, Hato T, Watanabe M, Horinouchi H, Sakai H, Kobayashi K, Iwazaki M. Biomed Res. 2024;45(2):91-101.
17. Dexamethasone restores TNF??-induced epithelial barrier dysfunction in primary rat alveolar epithelial cells. Kutsuzawa N, Ito Y, Kagawa S, Kohno C, Takiguchi H, Asano K. PLoS One. 2023 Dec 27;18(12):e0295684.
18. Administration of the GLP-1 receptor agonist exenatide in rats improves functional recovery after spinal cord injury by reducing endoplasmic reticulum stress. Nomura S, Katoh H, Yanagisawa S, Noguchi T, Okada K, Watanabe M. IBRO Neurosci Rep. 2023 Sep 11;15:225-234.
19. Replacement of pulmonary venous stent during Fontan operation. Ono S, Torii S, Ueda H. Cardiol Young. 2023 Dec;33(12):2670-2672.
20. Multiple intra-articular injections with adipose-derived stem cells for knee osteoarthritis cause severe arthritis with anti-histone H2B antibody production. Hosono Y, Kuwasawa A, Toyoda E, Nihei K, Sato S, Watanabe M, Sato M. Regen Ther. 2023 Jun 26;24:147-153.
21. Recombinant Laminin-511 Fragment (iMatrix-511) Coating Supports Maintenance of Human Nucleus Pulposus Progenitor Cells In Vitro. Soma H, Sakai D, Nakamura Y, Tamagawa S, Warita T, Schol J, Matsushita E, Naiki M, Sato M, Watanabe M. Int J Mol Sci. 2023 Nov 24;24(23):16713.
22. Poor Below Knee Runoff Impacts Femoropopliteal Stent Failure and Fluoropolymer Antithrombotic Effect in Healthy Swine Model. Nakamura N, Torii S, Aihara K, Noda S, Kato T, Nakazawa K, Ikari Y, Nakazawa G. Eur J Vasc Endovasc Surg. 2023 Nov;66(5):722-729.
23. Direct neuronal conversion of microglia/macrophages reinstates neurological function after stroke. Irie T, Matsuda T, Hayashi Y, Matsuda-Ito K, Kamiya A, Masuda T, Prinz M, Isobe N, Kira JI, Nakashima K. Proc Natl Acad Sci U S A. 2023 Oct 17;120(42):e2307972120.
24. Retrovirus-Derived RTL9 Plays an Important Role in Innate Antifungal Immunity in the Eutherian Brain. Ishino F, Itoh J, Irie M, Matsuzawa A, Naruse M, Suzuki T, Hiraoka Y, Kaneko-Ishino T. Int J Mol Sci. 2023 Oct 4;24(19):14884.
25. Neuronal SAM68 differentially regulates alternative last exon splicing and ensures proper synapse development and function. Darwish M, Ito M, Iijima Y, Takase A, Ayukawa N, Suzuki S, Tanaka M, Komori K, Kaida D, Iijima T. J Biol Chem. 2023 Oct;299(10):105168.
26. Aberrant Water Structure Dynamics in B16 Melanoma-Bearing Mice by Time Domain Refractometry Analysis. Furuhata K, Masuda H, Sato A, Miyata K, Shinyashiki N, Kita R, Imagawa K, Akamatsu T, Yagihara S. Biology (Basel). 2023 Sep 18;12(9):1250.
27. Proteomic profiling of sudden cardiac death with acquired cardiac hypertrophy. Kakimoto Y, Ueda A, Ito M, Tanaka M, Kubota T, Isozaki S, Osawa M. Int J Legal Med. 2023 Sep;137(5):1453-1461.
28. The hepatic niche leads to aggressive natural killer cell leukemia proliferation through the transferrin-transferrin receptor 1 axis. Kameda K, Yanagiya R, Miyatake Y, Carreras J, Higuchi H, Murayama H, Ishida T, Ito A, Iida S, Fukuhara N, Harigae H, Fujioka Y, Takahashi N, Wada H, Ishida F, Nakazawa H, Ishihara R, Murakami Y, Tagawa H, Matsuura T, Nakagawa S, Iwabuchi S, Hashimoto S, Imadome KI, Nakamura N, Ishizawa K, Kanda Y, Ando K, Kotani A. Blood. 2023 Jul 27;142(4):352-364.
29. Antigen/Adjuvant-Displaying Enveloped Viral Replica as a Self-Adjuvanting Anti-Breast-Cancer Vaccine Candidate. Ito K, Furukawa H, Inaba H, Ohshima S, Kametani Y, Maeki M, Tokeshi M, Huang X, Kabayama K, Manabe Y, Fukase K, Matsuura K. J Am Chem Soc. 2023 Jul 26;145(29):15838-15847.
30. Construction of the systemic anticancer immune environment in tumour-bearing humanized mouse by using liposome-encapsulated anti-programmed death ligand 1 antibody-conjugated progesterone. Kametani Y, Ito R, Ohshima S, Manabe Y, Ohno Y, Shimizu T, Yamada S, Katano N, Kirigaya D, Ito K, Matsumoto T, Tsuda B, Kashiwagi H, Goto Y, Yasuda A, Maeki M, Tokeshi M, Seki T, Fukase K, Mikami M, Ando K, Ishimoto H, Shiina T. Front Immunol. 2023 Jul 10;14:1173728.
31. Bovine bioprosthetic mitral valve tear with intra-leaflet hemorrhage. Imaoka T, Naganuma T, Torii S, Nakamura S. Eur Heart J Case Rep. 2023 Jul 4;7(7):ytad279.
32. Gas6 ameliorates intestinal mucosal immunosenescence to prevent the translocation of a gut pathobiont, Klebsiella pneumoniae, to the liver. Tsugawa H, Ohki T, Tsubaki S, Tanaka R, Matsuzaki J, Suzuki H, Hozumi K. PLoS Pathog. 2023 Jun 8;19(6):e1011139.
33. Differentiation Capacity of Porcine Skeletal Muscle-Derived Stem Cells as Intermediate Species between Mice and Humans. Tamaki T, Natsume T, Katoh A, Nakajima N, Saito K, Fukuzawa T, Otake M, Enya S, Kangawa A, Imai T, Tamaki M, Uchiyama Y. Int J Mol Sci. 2023 Jun 7;24(12):9862.
34. A pilot study of on-site evaluation as external quality assessment for ISO 15189 accreditation of laboratories performing next-generation sequencing oncology tests. Ravzanaadii M, Asai S, Kakizoe H, Natsagdorj ME, Miyachi H. J Clin Lab Anal. 2023 May;37(9-10):e24901.
35. Transferrin, insulin, and progesterone modulate intracellular concentrations of coenzyme Q and cholesterol, products of the mevalonate pathway, in undifferentiated PC12 cells. Nakamura A, Aida Y, Okamoto M, Maeda A, Nagao A, Kitatani K, Takekoshi S, Fujisawa A, Yamamoto Y, Kashiba M. J Clin Biochem Nutr. 2023 May;72(3):199-206.
36. A Method to Evaluate and Eliminate Fungal Contamination in Household Air Conditioners. Shiraishi Y, Harada K, Maeda C, Ogino F, Suzuki Y, Okada N, Tomomatsu K, Sekine Y, Yanagi U, Imanishi T, Oguma T, Asano K. Indoor Air. 2023 May 22;8984619.
37. Properties of hydrated poly(2-methoxyethyl acrylate) observed by carbon-13 nuclear magnetic resonance spectroscopy. Mochizuki A, Miwa Y, Yahata C, Saito H, Yoshiki Oda Y. International Journal of Polymer Analysis and Characterization. 2023 29 Aug; 28(5):523-535.
38. Pathological Analysis of Medial and Intimal Calcification in Lower Extremity Artery Disease: Impact of Hemodialysis. Kato T, Torii S, Nakamura N, Aihara K, Terabe Y, Iida O, Tokuda T, Nakama T,Kawahara Y, Miyamoto J, Saito T, Kamioka N, Murakami T, Ijichi T, Natsumeda M, Tanaka S, Ohno Y, Nakazawa G, Watanabe H, Ikari Y. JACC: Advances. 2023 Nov; 2(9):100656.
39. Onset Mechanisms and Prognosis of Neurally Mediated Syncope. Komiyama T, Ayabe K, Hasegawa M, Yoshikawa M, Sakama S, Lee K-H, Yagishita A, Amino M, Nagata E, Ikari Y, Yoshioka K, Kobayashi H. Reports. 2023; 6(4):56.
40. Carboxyhemoglobin Particle Infusion, but not Carbon Monoxide Inhalation ameliorates Myocardial Infarction via Attenuated Oxidative Stress and In Situ Inflammation in a Rat Model. Kawaguchi A, Tanaka T, Yamano M, Sumiyoshi H, Yamada Y, Kawaguchi G, Bergsland J. Medical Research Archives. 2023 29 Nov; 11(11).
41. De novo Biological Coronary Artery Bypass in a Rat Model: Case Report and the Concept of Hybrid Cardiovascular Regeneration. Kawaguchi T, Salybekov A, Yamano M, Sumiyoshi H, Kawaguchi G, Matsuda S, Sekine K, Shibata M, Yamada Y. Medical Research Archives. 2024 29 Feb; 12(2).
1. Histological evaluation of vascular changes after excimer laser angioplasty for neointimal formation after bare-metal stent implantation in rabbit iliac arteries. Nagamatsu H, Torii S, Aihara K, Nakazawa K, Nakamura N, Noda S, Sekino S, Yoshimachi F, Nakazawa G, Ikari Y. Cardiovasc Interv Ther. 2023 Apr;38(2):223-230.
2. Differences in Biologic Drug Effects and Distal Particulate Embolization in Three Paclitaxel-Coated Balloons for Femoropopliteal Lesions in a Rabbit Model. Yoshikawa M, Torii S, Aihara K, Ito M, Nakamura N, Noda S, Yoshikawa A, Utsunomiya S, Nakazawa Md G, Ikari Y. J Endovasc Ther. 2023 Mar 23:15266028231161215.
3. Bag-1 Protects Nucleus Pulposus Cells from Oxidative Stress by Interacting with HSP70. Suyama K, Sakai D, Hayashi S, Qu N, Terayama H, Kiyoshima D, Nagahori K, Watanabe M. Biomedicines. 2023 Mar 12;11(3):863.
4. Mutational Profile and Pathological Features of a Case of Interleukin-10 and RGS1-Positive Spindle Cell Variant Diffuse Large B-Cell Lymphoma. Carreras J, Kikuti YY, Miyaoka M, Hiraiwa S, Tomita S, Ikoma H, Kondo Y, Ito A, Nagase S, Miura H, Roncador G, Colomo L, Hamoudi R, Campo E, Nakamura N. Hematol Rep. 2023 Mar 12;15(1):188-200.
5. Homing of vertebral-delivered mesenchymal stromal cells for degenerative intervertebral discs repair - an in vivo proof-of-concept study. Schol J, Sakai D, Warita T, Nukaga T, Sako K, Wangler S, Tamagawa S, Zeiter S, Alini M, Grad S. JOR Spine. 2022 Nov 14;6(1):e1228.
6. Inositol pyrophosphate profiling reveals regulatory roles of IP6K2-dependent enhanced IP(7) metabolism in the enteric nervous system. Ito M, Fujii N, Kohara S, Hori S, Tanaka M, Wittwer C, Kikuchi K, Iijima T, Kakimoto Y, Hirabayashi K, Kurotaki D, Jessen HJ, Saiardi A, Nagata E. J Biol Chem. 2023 Mar;299(3):102928.
7. Adherent-invasive E. coli - induced specific IgA limits pathobiont localization to the epithelial niche in the gut. Tanaka R, Imai J, Tsugawa H, Eap KB, Yazawa M, Kaneko M, Ohno M, Sugihara K, Kitamoto S, Nagao-Kitamoto H, Barnich N, Matsushima M, Suzuki T, Kagawa T, Nishizaki Y, Suzuki H, Kamada N, Hozumi K. Front Microbiol. 2023 Feb 23;14:1031997.
8. Expression of hormone receptors is associated with specific immunological profiles of the breast cancer microenvironment. Hanamura T, Kitano S, Kagamu H, Yamashita M, Terao M, Okamura T, Kumaki N, Hozumi K, Iwamoto T, Honda C, Kurozumi S, Niikura N. Breast Cancer Res. 2023 Jan 31;25(1):13.
9. Mitochondrial Electron Transport Chain Complex II Dysfunction Causes Premature Aging of Hematopoietic Stem Cells. Harada K, Yahata T, Onizuka M, Ishii T, Aziz Ibrahim A, Kikkawa E, Gondo Y, Ando K. Stem Cells. 2023 Jan 30;41(1):39-49.
10. Effects of Genetic Mutation Sites in ADR Genes on Modern Chickens Produced and Domesticated by Artificial Selection. Komiyama T. Biology (Basel). 2023 Jan 20;12(2):169.
11. Improved Genome Editing via Oviductal Nucleic Acids Delivery (i-GONAD): Protocol Steps and Additional Notes. Sato M, Nakamura A, Sekiguchi M, Matsuwaki T, Miura H, Gurumurthy CB, Kakuta S, Ohtsuka M. Methods Mol Biol. 2023;2631:325-340.
12. Central nervous system specific high molecular weight ALS2/alsin homophilic complex is enriched in mouse brain synaptosomes. Sato K, Suzuki-Utsunomiya K, Mitsui S, Ono S, Shimakura K, Otomo A, Hadano S. Biochem Biophys Res Commun. 2023 Jan 1;638:168-175.
13. C-type lectin-like receptor (CLEC)-2, the ligand of podoplanin, induces morphological changes in podocytes. Tanaka K, Tanaka M, Watanabe N, Ito M, Pastan I, Koizumi M, Matsusaka T. Sci Rep. 2022 Dec 26;12(1):22356.
14. Thrombin cleaves recombinant soluble thrombomodulin into a lectin-like domain fragment and a fragment with protein C-activating cofactor activity. Yokoyama H, Tateishi K, Baba Y, Kobayashi A, Hashimoto M, Fukuda S, Yamao H, Maruyama T, Nakata M, Matsushita M. Biosci Trends. 2022 Dec 26;16(6):444-446.
15. De-erosion of X chromosome dosage compensation by the editing of XIST regulatory regions restores the differentiation potential in hPSCs. Motosugi N, Sugiyama A, Okada C, Otomo A, Umezawa A, Akutsu H, Hadano S, Fukuda A. Cell Rep Methods. 2022 Nov 29;2(12):100352.
16. Polydactyly-derived allogeneic chondrocyte cell-sheet transplantation with high tibial osteotomy as regenerative therapy for knee osteoarthritis. Hamahashi K, Toyoda E, Ishihara M, Mitani G, Takagaki T, Kaneshiro N, Maehara M, Takahashi T, Okada E, Watanabe A, Nakamura Y, Kato R, Matoba R, Takagi T, Akutsu H, Umezawa A, Kobayashi H, Akamatsu T, Yamato M, Okano T, Watanabe M, Sato M. NPJ Regen Med. 2022 Dec 16;7(1):71.
17. Heavy Ion Irradiation Reduces Vulnerability to Atrial Tachyarrhythmias　- Gap Junction and Sympathetic Neural Remodeling. Amino M, Yamazaki M, Yoshioka K, Kawabe N, Tanaka S, Shimokawa T, Niwa R, Tomii N, Kabuki S, Kunieda E, Yagishita A, Ikari Y, Kodama I. Circ J. 2022 Dec 6.
18. Transcription factor Zbtb1 interacts with bridging factor Lmo2 and maintains the T-lineage differentiation capacity of lymphoid progenitor cells. Koizumi M, Kama Y, Hirano KI, Endo Y, Tanaka T, Hozumi K, Hosokawa H. J Biol Chem. 2022 Nov;298(11):102506.
19. Podocytes are lost from glomeruli before completing apoptosis. Yamamoto K, Okabe M, Tanaka K, Yokoo T, Pastan I, Araoka T, Osafune K, Udagawa T, Koizumi M, Matsusaka T. Am J Physiol Renal Physiol. 2022 Nov 1;323(5):F515-F526.
20. Protective Effect of Ebselen on Ischemia-reperfusion Injury in Epigastric Skin Flaps in Rats. Kuroki T, Takekoshi S, Kitatani K, Kato C, Miyasaka M, Akamatsu T. Acta Histochem Cytochem. 2022 Oct 28;55(5):149-157.
21. Artificial Intelligence Predicted Overall Survival and Classified Mature B-Cell Neoplasms Based on Immuno-Oncology and Immune Checkpoint Panels. Carreras J, Roncador G, Hamoudi R. Cancers (Basel). 2022 Oct 28;14(21):5318.
22. Possible Glutathione Peroxidase 4-Independent Reduction of Phosphatidylcholine Hydroperoxide: Its Relevance to Ferroptosis. Kato C, Suzuki Y, Parida IS, Kato S, Yamasaki H, Takekoshi S, Nakagawa K. J Oleo Sci. 2022 Oct 28;71(11):1689-1694.
23. miR-4653-3p overexpression is associated with a poor prognosis of pancreatic ductal adenocarcinoma via HIPK2 downregulation. Hirabayashi K, Miyazawa M, Takanashi Y, Morimachi M, Kawanishi A, Saika T, Nakagohri T, Nakamura N. Sci Rep. 2022 Oct 26;12(1):17927.
24. CRISPR-KRISPR: a method to identify on-target and random insertion of donor DNAs and their characterization in knock-in mice. Tanaka M, Yokoyama K, Hayashi H, Isaki S, Kitatani K, Wang T, Kawata H, Matsuzawa H, Gurumurthy CB, Miura H, Ohtsuka M. Genome Biol. 2022 Oct 25;23(1):228.
25. PMEL p.Leu18del dilutes coat color of Kumamoto sub-breed of Japanese Brown cattle. Kimura S, Hatakeyama T, Koutaka T, Kubo K, Morita S, Eguchi K, Saitoh K, Yamauchi K, Imai S, Kashimura A, Inenaga T, Matsumoto H. BMC Genomics. 2022 Oct 7;23(1):694.
26. Foxc1 and Foxc2 are indispensable for the maintenance of nephron and stromal progenitors in the developing kidney. Motojima M, Tanaka M, Kume T. J Cell Sci. 2022 Oct 1;135(19):jcs260356.
27. A New Drug-Free Cancer Therapy Using Ultraviolet Pulsed Irradiation. PDT (PhotoDynamic Therapy) to PPT (Pulsed Photon Therapy). Itoh J, Itoh Y. Front Biosci (Schol Ed). 2022 Sep 30;14(4):27.
28. Effect of Neonicotinoid Pesticides on Japanese Water Systems: Review with Focus on Reproductive Toxicity. Terayama H, Sakabe K, Kiyoshima D, Qu N, Sato T, Suyama K, Hayashi S, Sakurai K, Todaka E, Mori C. Int J Mol Sci. 2022 Sep 30;23(19):11567.
29. Immunological imprint on peripheral blood in kidney transplant recipients after two doses of SARS-CoV-2 mRNA vaccination in Japan. Takiguchi S, Tomita Y, Uehara S, Tateishi K, Yamamoto N, Nakamura M. Front Med (Lausanne). 2022 Sep 28;9:999374.
30. High-progesterone environment preserves T cell competency by evading glucocorticoid effects on immune regulation. Kashiwagi H, Seki T, Oshima S, Ohno Y, Shimizu T, Yamada S, Katano N, Goto Y, Yasuda A, Tsuda B, Ito R, Izumi SI, Ishimoto H, Shiina T, Kametani Y. Front Immunol. 2022 Sep 20;13:1000728.
31. Retrovirus-derived RTL5 and RTL6 genes are novel constituents of the innate immune system in the eutherian brain. Irie M, Itoh J, Matsuzawa A, Ikawa M, Kiyonari H, Kihara M, Suzuki T, Hiraoka Y, Ishino F, Kaneko-Ishino T. Development. 2022 Sep 15;149(18):dev200976.
32. SQSTM1, a protective factor of SOD1-linked motor neuron disease, regulates the accumulation and distribution of ubiquitinated protein aggregates in neuron. Mitsui S, Otomo A, Sato K, Ishiyama M, Shimakura K, Okada-Yamaguchi C, Warabi E, Yanagawa T, Aoki M, Shang HF, Hadano S. Neurochem Int. 2022 Sep;158:105364.
33. Artificial Intelligence Analysis of Celiac Disease Using an Autoimmune Discovery Transcriptomic Panel Highlighted Pathogenic Genes including BTLA. Carreras J. Healthcare (Basel). 2022 Aug 16;10(8):1550.
34. Wall teichoic acid-dependent phagocytosis of intact cell walls of Lactiplantibacillus plantarum elicits IL-12 secretion from macrophages. Kojima N, Kojima S, Hosokawa S, Oda Y, Zenke D, Toura Y, Onohara E, Yokota SI, Nagaoka M, Kuroda Y. Front Microbiol. 2022 Aug 9;13:986396.
35. Use of anti-inhibin monoclonal antibody for increasing the litter size of mouse strains and its application to in vivo-genome editing technology†. Hasegawa A, Mochida K, Nakamura A, Miyagasako R, Ohtsuka M, Hatakeyama M, Ogura A. Biol Reprod. 2022 Aug 9;107(2):605-618.
36. Artificial Intelligence Analysis of Ulcerative Colitis Using an Autoimmune Discovery Transcriptomic Panel. Carreras J. Healthcare (Basel). 2022 Aug 5;10(8):1476.
37. Coccomyxa sp.KJ extract affects the fate of T cells stimulated by toxic shock syndrome toxin-1, a superantigen secreted by Staphylococcus aureus. Ohshima S, Komatsu S, Kashiwagi H, Goto Y, Ohno Y, Yamada S, Kanno A, Shimizu T, Seki T, Yasuda A, Kuno H, Kametani Y. Microbiol Immunol. 2022 Aug;66(8):394-402.
38. Protective effect of ebselen on bleomycin-induced lung fibrosis: analysis of the molecular mechanism of lung fibrosis mediated by oxidized diacylglycerol. Yagasaki H, Takekoshi S, Kitatani K, Kato C, Yamasaki H, Shioyama K, Tsuboi T, Matsuzaki T, Inagaki Y, Masuda R, Iwazaki M. Free Radic Res. 2022 Jul-Aug;56(7-8):473-482.
39. Precise immunological evaluation rationalizes the design of a self-adjuvanting vaccine composed of glycan antigen, TLR1/2 ligand, and T-helper cell epitope. Chang TC, Manabe Y, Ito K, Yamamoto R, Kabayama K, Ohshima S, Kametani Y, Fujimoto Y, Lin CC, Fukase K. RSC Adv. 2022 Jun 29;12(29):18985-18993.
40. Quantitative Evaluation of the Reduced Capacity of Skeletal Muscle Hypertrophy after Total Body Irradiation in Relation to Stem/Progenitor Cells. Fukuzawa T, Natsume T, Tamaki M, Imai T, Yamato I, Tamaki T. J Clin Med. 2022 Jun 28;11(13):3735.
41. Non-polyalanine repeat mutation in PHOX2B is detected in autopsy cases of sudden unexpected infant death. Ueda A, Osawa M, Naito H, Ochiai E, Kakimoto Y. PLoS One. 2022 Apr 29;17(4):e0267751.
42. RNA-seq and Mitochondrial DNA Analysis of Adrenal Gland Metastatic Tissue in a Patient with Renal Cell Carcinoma. Komiyama T, Kim H, Tanaka M, Isaki S, Yokoyama K, Miyajima A, Kobayashi H. Biology (Basel). 2022 Apr 13;11(4):589.
43. Secreted phospholipase A(2) modifies extracellular vesicles and accelerates B cell lymphoma. Kudo K, Miki Y, Carreras J, Nakayama S, Nakamoto Y, Ito M, Nagashima E, Yamamoto K, Higuchi H, Morita SY, Inoue A, Aoki J, Ando K, Nakamura N, Murakami M, Kotani A. Cell Metab. 2022 Apr 5;34(4):615-633.e8.
44. Epithelial-mesenchymal transition and bi- and multi-nucleated trophoblast cell formation in ovine conceptuses during the peri-implantation period. Yamada A, Ohtsuki K, Shiga N, Green JA, Matsuno Y, Imakawa K. J Reprod Dev. 2022 Apr 1;68(2):110-117.
45. Free d-Amino Acids in Salivary Gland in Rat. Yoshikawa M, Kan T, Shirose K, Watanabe M, Matsuda M, Ito K, Kawaguchi M. Biology (Basel). 2022 Mar 2;11(3):390.
46. Early reperfusion with hemoglobin vesicles into tracheal subepithelial capillaries in a mouse tracheal transplant model. Onozawa H, Kohno M, Hashimoto R, Oiwa K, Masuda R, Yamaguchi M, Hato T, Watanabe M, Horinouchi H, Sakai H, Kobayashi K, Iwazaki M. Biomed Res. 2022;43(4):137-144.
47. Multiplicity of sperm receptacles for securing the offspring genetic variability in a pelagic squid. Sato N, Ono H, Hirohashi N, Iwata Y. Marine Biology. 2023 Mar 27;170:51.
48. In vitro evaluation of the anti-diabetic potential of soymilk yogurt and identification of inhibitory compounds on the formation of advanced glycation end-products. Nakashima Y, Yamamoto N, Tsukioka R, Sugawa H, Ohshima R, Aoki K, Hibi T, Onuki K, Fukuchi Y, Yasuda S, Nagai R, Kinoshita H. Food Bioscience. 2022 Dec;50:102051.
49. Correlation of Axillary Artery Pressure and Phase of Esophageal Impedance in Chickens. Nakajima I, Kuwahira I, Hori S, Mitsuhashi K. J Multimed Inf Syst. 2022 Jun 30;9(2):161-170.
50. Systemic Infection of Gut Pathobiont Klebsiella pneumoniae Is Prevented by Gas6/Axl Signals in the Intestinal Epithelium. Nomura H, Terayama H, Kiyoshima D, Qu N, Shirose K, Tetsu S, Hayashi S, Sakabe K, Suzuki T. Applied Sciences. 2022; 12(20):10409.
51. Regulation of Renin Expression by Β1-Integrin in As4.1 Juxtaglomerular Line Cells. Saito N, Toyoda M, Kondo M, Abe M, Sanechika N, Kimura M, Sawada K, Fukagawa M. Biomedicines. 2023 Feb 9;11(2):501.
52. ROS1 as a possible prognostic biomarker of cervical adenocarcinoma: An exploratory analysis with next-generation sequencing. Machida H, Matsuo K, Tanaka M, Kitatani K, Takase A, Yokoyama K, Kajiwara H, Yasaka M, Ikeda M, Yoshida H, Hirasawa T, Mikami M. Gynecol Oncol. 2023 Apr;171:59-66.
1. Anti-HBV drug entecavir ameliorates DSS-induced colitis through PD-L1 induction. Yamamoto Y, Carreras J, Shimizu T, Kakizaki M, Kikuti YY, Roncador G, Nakamura N, Kotani A. Pharmacol Res. 2022 May;179:105918.
2. Dll1 Can Function as a Ligand of Notch1 and Notch2 in the Thymic Epithelium. Hirano KI, Hosokawa H, Yahata T, Ando K, Tanaka M, Imai J, Yazawa M, Ohtsuka M, Negishi N, Habu S, Sato T, Hozumi K. Front Immunol. 2022 Mar 17;13:852427.
3. Characterization of lncRNA functioning in ovine conceptuses and endometria during the peri-implantation period. Matsuno Y, Kusama K, Imakawa K. Biochem Biophys Res Commun. 2022 Feb 26;594:22-30.
4. Anti-tumor activity of the pan-RAF inhibitor TAK-580 in combination with KPT-330 (selinexor) in multiple myeloma. Suzuki R, Kitamura Y, Ogiya D, Ogawa Y, Kawada H, Ando K. Int J Hematol. 2022 Feb;115(2):233-243.
5. Two distinct Notch signals, Delta-like 4/Notch1 and Jagged-1/Notch2, antagonistically regulate chemical hepatocarcinogenesis in mice. Nakano Y, Nakao S, Sueoka M, Kasahara D, Tanno Y, Sumiyoshi H, Itoh T, Miyajima A, Hozumi K, Inagaki Y. Commun Biol. 2022 Jan 21;5(1):85.
6. Administration of mucuna beans (Mucuna pruriences (L.) DC. var. utilis) improves cognition and neuropathology of 3×Tg-AD mice. Konishi F, Furusho T, Soeda Y, Yamauchi J, Kobayashi S, Ito M, Araki T, Kogure S, Takashima A, Takekoshi S. Sci Rep. 2022 Jan 19;12(1):996.
7. Pterostilbene downregulates BCR/ABL and induces apoptosis of T315I-mutated BCR/ABL-positive leukemic cells. Kawakami S, Tsuma-Kaneko M, Sawanobori M, Uno T, Nakamura Y, Matsuzawa H, Suzuki R, Onizuka M, Yahata T, Naka K, Ando K, Kawada H. Sci Rep. 2022 Jan 13;12(1):704.
8. Transplantation of Fibroblast Sheets with Blood Mononuclear Cell Culture Exerts Cardioprotective Effects by Enhancing Anti-Inflammation and Vasculogenic Potential in Rat Experimental Autoimmune Myocarditis Model. Sekine K, Kawaguchi AT, Miyazawa M, Hanawa H, Matsuda S, Tamaki T, Asahara T, Masuda H. Biology (Basel). 2022 Jan 10;11(1):106.
9. Leptin gene contributes to beef marbling standard, meat brightness, meat firmness, and beef fat standard of the Kumamoto sub-breed of Japanese Brown cattle. Matsumoto H, Kimura S, Nagai Y, Fukuda Y, Miyazaki K, Imai S, Inenaga T, Kashimura A. Anim Sci J. 2022 Jan;93(1):e13698.
10. High-throughput quantitative analysis of axonal transport in cultured neurons from SOD1(H46R) ALS mice by using a microfluidic device. Otomo A, Ono S, Sato K, Mitsui S, Shimakura K, Kimura H, Hadano S. Neurosci Res. 2022 Jan;174:46-52.
11. A potential pathogenic association between periodontal disease and Crohn's disease. Imai J, Ichikawa H, Kitamoto S, Golob JL, Kaneko M, Nagata J, Takahashi M, Gillilland MG 3rd, Tanaka R, Nagao-Kitamoto H, Hayashi A, Sugihara K, Bishu S, Tsuda S, Ito H, Kojima S, Karakida K, Matsushima M, Suzuki T, Hozumi K, Watanabe N, Giannobile WV, Shirai T, Suzuki H, Kamada N. JCI Insight. 2021 Dec 8;6(23):e148543.
12. Evaluation of Erastin as a Therapeutic Agent Under Hypoxic Conditions in Pancreatic Cancer Cells. Owada S, Endo H, Shida Y, Kinoue T, Furuya H, Tatemichi M. Anticancer Res. 2021 Dec;41(12):6051-6059.
13. External administration of moon jellyfish collagen solution accelerates physiological wound healing and improves delayed wound closure in diabetic model mice. Sumiyoshi H, Okamura Y, Kawaguchi AT, Kubota T, Endo H, Yanagawa T, Yasuda J, Matsuki Y, Nakao S, Inagaki Y. Regen Ther. 2021 Jul 19;18:223-230.
14. Modification of exosomes with carbonate apatite and a glycan polymer improves transduction efficiency and target cell selectivity. Matsuki Y, Yanagawa T, Sumiyoshi H, Yasuda J, Nakao S, Goto M, Shibata-Seki T, Akaike T, Inagaki Y. Biochem Biophys Res Commun. 2021 Oct 27;583:93-99.
15. Human hepatocyte-derived extracellular vesicles attenuate the carbon tetrachloride-induced acute liver injury in mice. Kakizaki M, Yamamoto Y, Nakayama S, Kameda K, Nagashima E, Ito M, Suyama T, Matsuzaki Y, Chiba T, Sumiyoshi H, Inagaki Y, Kotani A. Cell Death Dis. 2021 Oct 27;12(11):1010.
16. Extracellular Vesicles Derived From Regeneration Associated Cells Preserve Heart Function After Ischemia-Induced Injury. Salybekov AA, Salybekova A, Sheng Y, Shinozaki Y, Yokoyama K, Kobayashi S, Asahara T. Front Cardiovasc Med. 2021 Oct 20;8:754254.
17. Kruppel-like factor 15 induces the development of mature hepatocyte-like cells from hepatoblasts. Anzai K, Tsuruya K, Ida K, Kagawa T, Inagaki Y, Kamiya A. Sci Rep. 2021 Sep 17;11(1):18551.
18. Clinical Significance of the Head-Up Tilt Test in Improving Prognosis in Patients with Possible Neurally Mediated Syncope. Ayabe K, Komiyama T, Hasegawa M, Sakai T, Morise M, Sakama S, Yagishita A, Amino M, Ikari Y, Yoshioka K. Biology (Basel). 2021 Sep 15;10(9):919.
19. De novo DNA methyltransferases DNMT3A and DNMT3B are essential for XIST silencing for erosion of dosage compensation in pluripotent stem cells. Fukuda A, Hazelbaker DZ, Motosugi N, Hao J, Limone F, Beccard A, Mazzucato P, Messana A, Okada C, San Juan IG, Qian M, Umezawa A, Akutsu H, Barrett LE, Eggan K. Stem Cell Reports. 2021 Sep 14;16(9):2138-2148.
20. Antiplatelet Effect of Single Antiplatelet Therapy With Prasugrel and Oral Anticoagulation After Stent Implantation in a Rabbit Arteriovenous Shunt Model. Torii S, Yamamoto T, Nakamura N, Ijichi T, Yoshikawa A, Ito Y, Sugidachi A, Ikari Y, Nakazawa G. Circ Rep. 2021 Aug 7;3(9):504-510.
21. The N-terminal intrinsically disordered region mediates intracellular localization and self-oligomerization of ALS2. Shimakura K, Sato K, Mitsui S, Ono S, Otomo A, Hadano S. Biochem Biophys Res Commun. 2021 Sep 10;569:106-111.
22. Non-coding RNAs and lipids mediate the function of extracellular vesicles in cancer cross-talk. Kotani A, Ito M, Kudo K. Semin Cancer Biol. 2021 Sep;74:121-133.
23. Comparison of properties determined using electromechanical assessment (Arthro-BST^TM) with macroscopic and histological properties in symptomatic human articular cartilage of the hip. Ukai T, Sato M, Wasai S, Takahashi T, Omura H, Watanabe M. Arthritis Res Ther. 2021 Aug 31;23(1):227.
24. Notch signaling supports the appearance of follicular helper T cells in the Peyer's patches concomitantly with the reduction of regulatory T cells. Yazawa M, Hosokawa H, Koizumi M, Hirano KI, Imai J, Hozumi K. Int Immunol. 2021 Aug 23;33(9):469-478.
25. LMO2 is essential to maintain the ability of progenitors to differentiate into T-cell lineage in mice. Hirano KI, Hosokawa H, Koizumi M, Endo Y, Yahata T, Ando K, Hozumi K. Elife. 2021 Aug 12;10:e68227.
26. Stage-specific action of Runx1 and GATA3 controls silencing of PU.1 expression in mouse pro-T cells. Hosokawa H, Koizumi M, Masuhara K, Romero-Wolf M, Tanaka T, Nakayama T, Rothenberg EV. J Exp Med. 2021 Aug 2;218(8):e20202648.
27. CD45RA^-CD25^highCD127^-CD4⁺ activated regulatory T cells are correlated with de novo donor-specific anti-HLA antibody formation after kidney transplantation in standard immunosuppression. Tomita Y, Ishida H, Uehara S, Takiguchi S, Sato T, Nakamura M. Int Immunopharmacol. 2021 Aug;97:107661.
28. Par3 and ZO-1 Membrane Clustering is an Indicator of Poor Prognosis in Lung Squamous Cell Carcinoma. Nito M, Takekoshi S, Kitatani K, Matsuzaki T, Yagasaki H, Tsuboi T, Nakano K, Shioyama K, Masuda R, Iwazaki M. Tokai J Exp Clin Med. 2021 Jul 20;46(2):110-117.
29. Distinct Expression of SLM2 Underlies Splicing-Dependent Trans-Synaptic Signaling of Neurexin Across GABAergic Neuron Subtypes. Sato Y, Iijima Y, Darwish M, Sato T, Iijima T. Neurochem Res. 2021 Jul 1.
30. Diagnosis and prevention of the vasodepressor type of neurally mediated syncope in Japanese patients. Hasegawa M, Komiyama T, Ayabe K, Sakama S, Sakai T, Lee KH, Morise M, Yagishita A, Amino M, Sasaki A, Nagata E, Kobayashi H, Yoshioka K, Ikari Y. PLoS One. 2021 Jun 25;16(6):e0251450.
31. Plasminogen activator inhibitor type-1 is a negative regulator of hematopoietic regeneration in the adipocyte-rich bone marrow microenvironment. Harada K, Yahata T, Onizuka M, Ibrahim AA, Kikkawa E, Miyata T, Ando K. Biochem Biophys Res Commun. 2021 Jun 11;557:180-186.
32. Deletion of lncRNA XACT does not change expression dosage of X-linked genes, but affects differentiation potential in hPSCs. Motosugi N, Okada C, Sugiyama A, Kawasaki T, Kimura M, Shiina T, Umezawa A, Akutsu H, Fukuda A. Cell Rep. 2021 Jun 8;35(10):109222.
33. Reduced PHOX2B stability causes axonal growth impairment in motor neurons with TARDBP mutations. Mitsuzawa S, Suzuki N, Akiyama T, Ishikawa M, Sone T, Kawada J, Funayama R, Shirota M, Mitsuhashi H, Morimoto S, Ikeda K, Shijo T, Ohno A, Nakamura N, Ono H, Ono R, Osana S, Nakagawa T, Nishiyama A, Izumi R, Kaneda S, Ikeuchi Y, Nakayama K, Fujii T, Warita H, Okano H, Aoki M. Stem Cell Reports. 2021 Jun 8;16(6):1527-1541.
34. Examination of gender differences in patients with takotsubo syndrome according to left ventricular biopsy: two case reports. Murakami T, Komiyama T, Matsumoto S, Kajiwara H, Kobayashi H, Ikari Y. J Med Case Rep. 2021 May 21;15(1):281.
35. Response to correspondence on "Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation". Gurumurthy CB, O'Brien AR, Quadros RM, Adams J Jr, Alcaide P, Ayabe S, Ballard J, Batra SK, Beauchamp MC, Becker KA, Bernas G, Brough D, Carrillo-Salinas F, Chan W, Chen H, Dawson R, DeMambro V, D'Hont J, Dibb K, Eudy JD, Gan L, Gao J, Gonzales A, Guntur A, Guo H, Harms DW, Harrington A, Hentges KE, Humphreys N, Imai S, Ishii H, Iwama M, Jonasch E, Karolak M, Keavney B, Khin NC, Konno M, Kotani Y, Kunihiro Y, Lakshmanan I, Larochelle C, Lawrence CB, Li L, Lindner V, Liu XD, Lopez-Castejon G, Loudon A, Lowe J, Jerome-Majeweska L, Matsusaka T, Miura H, Miyasaka Y, Morpurgo B, Motyl K, Nabeshima YI, Nakade K, Nakashiba T, Nakashima K, Obata Y, Ogiwara S, Ouellet M, Oxburgh L, Piltz S, Pinz I, Ponnusamy MP, Ray D, Redder RJ, Rosen CJ, Ross N, Ruhe MT, Ryzhova L, Salvador AM, Alam SS, Sedlacek R, Sharma K, Smith C, Staes K, Starrs L, Sugiyama F, Takahashi S, Tanaka T, Trafford A, Uno Y, Vanhoutte L, Vanrockeghem F, Willis BJ, Wright CS, Yamauchi Y, Yi X, Yoshimi K, Zhang X, Zhang Y, Ohtsuka M, Das S, Garry DJ, Hochepied T, Thomas P, Parker-Thornburg J, Adamson AD, Yoshiki A, et al. Genome Biol. 2021 Apr 7;22(1):99.
36. Somatic mutations in oral squamous cell carcinomas in 98 Japanese patients and their clinical implications. Osawa Y, Aoyama KI, Hosomichi K, Uchibori M, Tajima A, Kimura M, Ota Y. Cancer Treat Res Commun. 2021;29:100456.
37. Tropomyosin-related kinase B (TrkB) full-length isoform is related to advanced-stage clear cell ovarian cancer (CCOC). Goto Y, Kametani Y, Auguste A, Almamari T, LeFormal A, Izumi S, Genestie C, Ishimoto H, Mikami M. Eur J Gynaecol Oncol. 2021 Oct 16;42(5):899–908.
38. Genetic diversities of commercially harvested jellyfish, Rhopilema hispidum and Lobonemoides robustus in Southeast Asia. Iida A, Nohara K, Yusoff F, Srinui K, Ha T, Ohtsuka S, Metillo E, Pagliawan H, Nishikawa J. Plankton Benthos Res. 2021 Nov 17;16(4):308–317.
39. Infection of a species of digenean in common octopus Octopus sinensis in Japan. Izumi S, Akiyama N, Suzumura Y, Ogawa K. Fish Pathology. 2021 Dec 15;56(4):199-204.
40. Potential UV-Protective Effect of Freestanding Biodegradable Nanosheet-Based Sunscreen Preparations in XPA-Deficient Mice Hatanaka T, Ramphai K, Takimoto S, Kanda H, Motosugi N, Kimura M, Mabuchi T, Oyama M, Takeuchi T, Okamura Y. Pharmaceutics. 2022 Feb 17;14(2):431.
41. Free d-Amino Acids in Salivary Gland in Rat. Yoshikawa M, Kan T, Shirose K, Watanabe M, Matsuda M, Ito K, Kawaguchi M. Biology (Basel). 2022 Mar 2;11(3):390.
42. Lack of expression of LMO2 clone SP51 identifies MYC rearrangements in aggressive large B-cell lymphomas. Vazquez I, Papaleo N, Lop J, Puiggros A, Sanchez-Gonzalez B, Diez-Feijoo R, Gimeno E, Andrade-Campos M, Salar A, Espinet B, Salido M, Tapia G, Carreras J, Ferrer A, Arenillas L, Calvo X, Colomo L. Virchows Arch. 2021 Dec;479(6):1073-1078.
43. High PTX3 expression is associated with a poor prognosis in diffuse large B-cell lymphoma. Carreras J, Kikuti YY, Hiraiwa S, Miyaoka M, Tomita S, Ikoma H, Ito A, Kondo Y, Itoh J, Roncador G, Martinez A, Colomo L, Hamoudi R, Ando K, Nakamura N. Cancer Sci. 2022 Jan;113(1):334-348.
44. Artificial Neural Networks Predicted the Overall Survival and Molecular Subtypes of Diffuse Large B-Cell Lymphoma Using a Pancancer Immune-Oncology Panel. Carreras J, Hiraiwa S, Kikuti YY, Miyaoka M, Tomita S, Ikoma H, Ito A, Kondo Y, Roncador G, Garcia JF, Ando K, Hamoudi R, Nakamura N. Cancers (Basel). 2021 Dec 20;13(24):6384.
45. Artificial Intelligence Analysis of Gene Expression Predicted the Overall Survival of Mantle Cell Lymphoma and a Large Pan-Cancer Series. Carreras J, Nakamura N, Hamoudi R. Healthcare (Basel). 2022 Jan 14;10(1):155.
46. High Expression of Caspase-8 Associated with Improved Survival in Diffuse Large B-Cell Lymphoma: Machine Learning and Artificial Neural Networks Analyses. Carreras J, Kikuti YY, Roncador G, Miyaoka M, Hiraiwa S, Tomita S, Ikoma H, Kondo Y, Ito A, Shiraiwa S, et al. BioMedInformatics. 2021; 1(1):18-46.
47. Indirect podocyte injury manifested in a partial podocytectomy mouse model. Okabe M, Yamamoto K, Miyazaki Y, Motojima M, Ohtsuka M, Pastan I, Yokoo T, Matsusaka T. Am J Physiol Renal Physiol. 2021 May 1;320(5):F922-F933.
48. Stereospecificity of hydride transfer and molecular docking in FMN-dependent NADH-indigo reductase of Bacillus smithii. Yoneda K, Sakuraba H, Araki T, Ohshima T. FEBS Open Bio. 2021 Jul;11(7):1981-1986.
• 職員の研究活動
• 2023年度研究活動

教育支援

委員会

• 東海大学遺伝子組換え実験安全委員会
• 東海大学動物実験委員会
• 東海大学伊勢原キャンパス動物実験専門委員会
(アニマルウェルフェア小委員会、感染対策小委員会、災害時対策小委員会、飼育SOP小委員会、新動物施設への動物移動小委員会)
• 安全衛生委員会
• 化学物質管理委員会
• 自己点検評価委員会Area.6小委員会
• バイオセーフティ委員会
• バイオバンクWG
• 教育研究共同利用機器運営委員会
• 生命科学統合支援室連絡協議会
• 伊勢原CGD新1号館新築事業プロジェクト委員会

プロジェクト

• 日立ハイテク3社との研究装置の遠隔利用に関する実証実験プロジェクト

東海大学では、遠隔保守とクラウドの活用によって全国５キャンパスに分散する研究装置の有効利用の促進に向けて、2023年2月に日立ハイテクグループ３社と共同実証事業の連携協定を締結しました。

本協定は、５キャンパス間で研究装置を遠隔利用できる各種ITツールやアプリケーションの改善・新規開発を視野に入れたもので、実証実験を共同で推進していきます。

伊勢原キャンパスでは、当室の技術職員がプロジェクトに参加し、生命科学統合支援センターに設置されている下記装置のリモートシステム導入および実証試験を進めています。

• 走査型電子顕微鏡 (JEOL)
• 透過型電子顕微鏡 (JEOL)
• 液体クロマトグラフィー質量分析装置 (SHIMADZU)